General Cell Based Assays
Eurofins Discoverx cAMP Hunter™ Human GLP-1 (GLP-1 Receptor) Gs Cell-Based Assay Kit (HEK 293)
The cAMP Hunter™ Human GLP-1 (GLP1R) Gs Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure GLP1R (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LXR beta-NCoR1 Nuclear Receptor Protein Interaction Cell-Based Assay Kit (HEK 293)
The PathHunter Human LXR beta-NCoR1 Nuclear Receptor Stable Cell Line Protein Interaction Assay (HEK 293) contains a stable clonal cell line used to measure activated LXRβ-NCoR1 nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MTNR1A Total GPCR Internalization Cell-Based Assay Kit (DLD1)
The PathHunter Human MTNR1A Stable Cell Line Total GPCR Internalization Assay (DLD1) contains a stable clonal cell line used to measure MTNR1A (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human c-Ret-GF Ralpha 1 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human c-Ret-GFR alpha 1 Stable Cell Line Functional Kinase Assay (U2OS) measures c-Ret-GFRα1 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mHTR2C (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2A (5-HT2A) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2A (5-HT2A) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR2A (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCL1 (CCR8) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CCL1 (CCR8) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR8 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human GPR1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure GPR1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse CTLA4 Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Mouse CTLA4 (SHP1) Signaling Stable Cell Line Assay (Jurkat) measures CTLA4 signal by recruitment of SH2 domain protein to the activated receptor. Please note this product expresses the mouse version of CTLA-4. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPS Signaling Reporter Cell-Based Assay Kit (THP-1)
The PathHunter Human LPS Signaling NF-kB Reporter Stable Cell Line Assay (THP-1) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human CRHR1 Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CRHR1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CRHR1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx SPRINTer™ Human BRD4 Targeted Protein Degradation Cell-Based Assay Kit (K562)
The SPRINTer™ Human BRD4 Targeted Protein Degradation Stable Cell Line Assay (K562) contains a stable clonal cell line used for monitoring drug-induced protein turnover of BRD4, supporting TPD studies. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCK2 (CCKBR) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CCK2 (CCKBR) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCKBR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MCP-1 (CCR2) Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human MCP-1 (CCR2) Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCR2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AM2 (CALCRL-RAMP3) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human AM2 (CALCRL-RAMP3) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CALCRL (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.